關於 c-kit ，我們在網路上蒐集到這些相關的討論、資訊與評價

#11. KIT gene: MedlinePlus Genetics

Receptor tyrosine kinases transmit signals from the cell surface into the cell through a process called signal transduction. The KIT protein is ...

#12. The C-Kit Receptor-Mediated Signal Transduction and Tumor ...

The human receptor tyrosine kinase (RTK) c-kit (also referred to as stem cell factor receptor or CD117) was identified and characterized in 1987 as the cellular ...

#13. CD117 - an overview | ScienceDirect Topics

CD117 (c-kit) is a transmembrane tyrosine kinase receptor that has been immunolocalized in various neoplasms, the most notable of which is gastrointestinal ...

#14. c-Kit抑制剂

Sorafenib (BAY 43-9006) tosylate是Raf-1和B-Raf的多重激酶抑制剂，无细胞试验中IC50分别为6 nM和22 nM。Sorafenib 还可抑制VEGFR-2、VEGFR-3、PDGFR-β、Flt-3和c-KIT， ...

#15. Reassessment of c-Kit in Cardiac Cells - AHA Journals

c -Kit (CD117) is a type III receptor tyrosine kinase that activates a downstream signaling cascade on binding to stem cell factor.

#16. CD117 (c-Kit) Antibody, APC (17-1171-82) - Thermo Fisher ...

Invitrogen Anti-CD117 (c-Kit) Monoclonal (2B8), eBioscience™, Catalog # 17-1171-82. Tested in Flow Cytometry (Flow) applications. This antibody reacts with ...

#17. The Proto-oncogene c-Kit Inhibits Tumor Growth by Behaving ...

c -Kit, a well-known oncogene, actively triggers cell death in cancer cell lines d c-Kit triggers cell death unless engaged by its ligand ...

#18. PE anti-mouse CD117 (c-Kit) Antibody - BioLegend

PE anti-mouse CD117 (c-Kit) Antibody - CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR).

#19. c-Kit Protein Overview: Sequence, Structure, Function and ...

The tyrosine kinase receptor KIT and its ligand, KITLG (184745), function in hematopoiesis, melanogenesis, and gametogenesis (Rothschild et al., 2003). c-Kit ...

#20. MGI:96677 - KIT proto-oncogene receptor tyrosine kinase

View mouse Kit Chr5:75735647-75817382 with: phenotypes, sequences, polymorphisms, ... belly-spot, CD117, c-KIT, Dominant white spotting, Gsfsco1, Gsfsco5, ...

#21. Human KIT / c-KIT / CD117 ELISA Kit - 亞旭生物科技

分子 : KIT. 抗原貨號 : 11996-H08H. 產品介绍 : For the quantitative determination of Human KIT / c-KIT / CD117 concentration in serum. 線性範圍: 39-2500.

#22. c-kit ELISA Kits | Biocompare

Listed are ELISA Kits for the detection of c-kit, an alias name of KIT proto-oncogene, receptor tyrosine kinase. The human protein, encoded by ...

#23. Phospho-c-Kit (Tyr719) Antibody#3391 - Cell Signaling ...

Western Blotting Image 1: Phospho-c-Kit (Tyr719) Antibody Western blot analysis of extracts from MO7e cells, untreated or stimulated with SCF #9907 (50 ...

#24. c-kit受体_百度百科

CD117, also called KIT or C-kit receptor, is a cytokine receptor expressed on the surface of hematopoietic stem cells as well as other cell types.

#25. c-Kit Inhibition | c-Kit Mutation | c-Kit Inhibitor Review - Selleck ...

c -Kit inhibitors (inhibiting targets of signaling pathways) used for various assays, some have entered clinical trials, which would be new cancer therapies.

#26. High c-Kit expression identifies hematopoietic stem cells with ...

To determine if c-Kithi HSCs produced functional, platelet-forming megakaryocytes, we assessed polyploid megakaryocyte formation in the bone ...

#27. c-kit Ligand and Flt3 Ligand: Stem/Progenitor Cell Factors ...

11,12 The c-kit protein has the same general structure as four other tyrosine kinase receptors: c-fms, the receptor for macrophage colony- ...

#28. KIT PROTOONCOGENE, RECEPTOR TYROSINE KINASE

(2001) identified heterozygosity for a 1859T-C transition in the KIT gene, resulting in a val620-to-ala (V620A) substitution in the intracellular tyrosine ...

#29. 原發性子宮頸腺癌c-Kit基因表現但無合併該基因突變

中文：原發性子宮頸腺癌c-Kit基因表現但無合併該基因突變。 英文：Mutation-free expression of c-Kit proto-oncogene in primary adenocarcinoma of ...

#30. c-Kit | Inhibitors | MedChemExpress

c -Kit (CD117, KIT or SCFR), a type III receptor tyrosine kinase (RTK), is the receptor for stem cell factor (SCF). c-Kit binding to SCF activates signaling ...

#31. 偵測c-kit基因在犬肥大細胞瘤中的突變情形

因c-kit基因突變引起的KIT蛋白持續活化，在犬肥大細胞瘤(mast cell tumors) 的腫瘤生成中扮演著重要角色。而帶有c-kit基因突變的犬肥大細胞瘤較容易對於酪胺酸激酶抑制 ...

#32. c-KIT Mutation Analysis in Tumors of Hematopoietic Tissue

c -KIT mutations are reported in nearly all systemic mastocytosis, 20% to 40% core-binding factor (CBF) acute myeloid leukemia (AML), and approximately 20% high- ...

#33. EpiTect Hi-C Kit (US) - QIAGEN

EpiTect Hi-C Kit (US). A single-box solution for high-resolution mapping of chromatin folding. Features. All-inclusive ...

#34. Expression and localisation of c-kit and KITL in the adult ...

The c-kit/kit ligand (KITL) signalling axis is an essential component of ovarian folliculogenesis in mammals, but little is known about ...

#35. CD117 (c-kit) Antibodies - Beckman Coulter

CD117 (Stem Cell Factor Receptor, SCFR, mast-cell-Kit, and steel factor receptor) is a 145 kDa transmembrane glycoprotein encoded by the ckit protooncogene.

#36. Detecting c-Kit Mutations - MSU College of Veterinary Medicine

Tumors in which mutations in the c-Kit gene have been detected include canine and feline mast cell tumors (MCTs) and canine gastrointestinal stromal tumors ( ...

#37. Tumor estromal gástrico cístico C-kit negativo - SciELO - Brasil

Tumor estromal gástrico cístico C-kit negativo. Cystic gastric stromal tumor negative C-Kit. Leandro C. Barchi; Joaquim Gama-Rodrigues; Fábio Apm Carvalho; ...

#38. Preclinical Antitumor Activity of a Novel Anti–c-KIT Antibody ...

Purpose: c-KIT overexpression is well recognized in cancers such as gastrointestinal stromal tumors (GIST), small cell lung cancer (SCLC), ...

#39. Dovetail® Micro-C Kit

The Micro-C kit uses micrococcal nuclease (MNase) to digest chromatin prior to proximity ligation to generate ultra-high-resolution 3D genome architecture ...

#40. The effect of c-Kit inhibition on mast cells in skin, colon, and ...

Stem Cell Factor (SCF) signaling via its receptor tyrosine kinase, c-Kit, is vital for mast cell development, function and survival.

#41. Mast Cell Leukaemia: c-KIT Mutations Are Not Always Positive

Mast cell leukemia (MCL) is a rare and aggressive disease with poor prognosis and short survival time. D816V c-KIT mutation is the most frequent molecular ...

#42. Discovery of Conformational Control Inhibitors Switching off ...

Moreover, 10a can effectively inhibit various c-KIT mutants and the proliferation of several GIST cell lines. The distinct binding features and ...

#43. c-KIT - RTK - Enzyme Linked Receptors - Axon Medchem

Axon ID Name From price 1419 AB 1010 €70.00 1638 ABT 869 €85.00 1414 AG 013736 €50.00

#44. C-kit Gene Product (CD117) Immunoreactivity in Canine and ...

Received for publication January 14, 2004; accepted January. 28, 2004 (4B6258). KEY WORDS. CD117 c-kit dog cat immunohistochemistry mast cell tumors.

#45. c-Kit Expression and Stem Cell Factor-Induced Hematopoietic ...

Abstract. Expression of c-Kit (CD117) and stem cell factor/c-Kit-mediated cell proliferation were tested in vitro in young and old B6D2F1 mice to study the ...

#46. Detecting Secondary C-KIT Mutations in the Peripheral Blood ...

Keywords: Cell-free DNACirculating tumor DNAGastrointestinal stromal tumorC-KIT mutationNext-generation sequencing ...

#47. Gain-of-Function Mutations of c-kit ... - Science

Sequencing of c-kit complementary DNA, which encodes a proto-oncogenic receptor tyrosine kinase (KIT), from five GISTs revealed mutations in the region ...

#48. 數位小兔【SENNHEISER XS Lav USB-C Kit 森海領夾式麥克風 ...

商品特色◇ ◇ ◇ ☆ XS Lav USB-C是移動設備和計算機上增強對話應用程序的完美伴侶。 ☆ XS Lav 配備全指向夾式麥克風和2 m (6.6') 電纜，為您的採訪、演示、播客等 ...

#49. c-Kit | My Cancer

c -Kit. Biomarker Abbreviation: c-Kit. Definition: tyrosine-protein kinase Kit, also known as CD117 or mast/stem cell growth factor receptor (SCFR) - a ...

#50. The stem cell factor (SCF)/c-KIT signalling in testis and ...

The SCF/c-KIT interaction leads to receptor dimerization, activation of kinase activity and initiation of several signal transduction pathways ...

#51. KIT (c-KIT) Mutation Analysis | NeoGenomics Laboratories

c -KIT Mutation Analysis. Methodology. Molecular. Test Description. Bi-directional sequencing of KIT exons 8, 9, 11, 13 and 17 for detection of activating ...

#52. Activating c-KIT mutations in a subset of thymic carcinoma and ...

To analyze a multi-institutional series of type C thymic carcinomas (TCs) (including neuroendocrine tumors), focusing on the expression and mutations of c-KIT.

#53. c-KIT Mutation Analysis, Cell Based | Test Detail

c -KIT Mutation Analysis, Cell Based - Activating c-KIT mutations have been indentified in various human cancers. c-KIT exon 8 and 17 mutations have been ...

#54. C-Kit Promotes Growth and Migration of Human Cardiac ...

A recent phase I clinical trial (SCIPIO) has shown that autologous c-kit+ cardiac progenitor cells (CPCs) improve cardiac function and ...

#55. Stem Cell Factor/c-kit Signaling Promotes the Survival ...

c -kit receptor tyrosine kinase is a marker of progenitor cells, which differentiate into blood and/or vascular endothelial cells, and has an important role ...

#56. c-KIT Kinase Enzyme System - Promega Corporation

c -KIT is a proto-oncogene and a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-KIT was first identified as ...

#57. Triple C Kit - Scope Shop

This Triple C Kit includes the Triple C Manual, CD (Now provided on a USB stick) and 20 Checklists. The Triple C Checklist of Communication Competencies is ...

#58. 1PKG: Structure of a c-Kit Kinase Product Complex - RCSB PDB

The c-Kit proto-oncogene is a receptor protein-tyrosine kinase associated with several highly malignant human cancers.

#59. Glycoprep-C Kit Combination pack - NPS MedicineWise

Glycoprep-C Kit Combination pack. Active ingredient. Potassium chloride; Macrogol 3350; Sodium sulfate; Sodium chloride; Citric acid; Magnesium carbonate ...

#60. Activating mutations in c-KIT and PDGFRα are exclusively ...

tyrosine kinase receptor, c-KIT, platelet derived growth factor receptor, activating mutations,. Imatinib mesylate, GIST, Gleevec, therapy response.

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#62. The clinical significance of c-Kit mutations in metastatic oral ...

c -Kit mutation has been detected in various mucosal melanomas [19, 20], but it remains unclear whether it is a prognostic factor or therapeutic ...

#63. Emergency Equipment - The Chlorine Institute

Emergency Kit "C" is designed for use with the standard DOT 105J500W chlorine tank car, DOT MC331 chlorine cargo tank and DOT 51 portable tank in chlorine ...

#64. 內科-腸胃道基質瘤,臨床醫學教室 - 高點醫護網

遺傳上存在c-kit基因突變。食道GIST預後最佳，而小腸預後最差。術後容易復發，但接受標靶藥物「基利克Gleevec」的輔助性 ...

#65. 비인강암에서 c-kit 단백의 발현 및 유전자 변이의 임상적 의미

Clinical Significance of c-kit Protein Expression and c-kit Gene Mutation in ... The proto-oncogene c-kit is a receptor tyrosine kinase recognized to ...

#66. Corrosion Toolkit (cKit™) | NACE Foundation

The Corrosion Toolkit (cKit™) was developed in 2005 by the NACE Foundation as a fun and stimulating learning experience for students, as well as hands-on ...

#67. Bodily C-Kit for C-Section & Postpartum Recovery

This curated c-section recovery kit from Bodily has all the essentials to support healing in the days and weeks after a cesarean birth, from postpartum ...

#68. Colonoscopy: GlycoPrep-C® Kit bowel preparation (Extended)

Kit contents: Bisacodyl tablets (x3 5mg tablets in a blister pack); Magnesium Citrate sachet x1; GlycoPrep-C sachet x1 (210g); A ...

#69. KIT - WikiSkripta

KIT je gen pro tyrozinkinázový receptor (CD117, SCFR, c-Kit) pro růstový faktor SCF. Zároveň jde o protoonkogen, který má i svůj virový ...

#70. Familial Gastrointestinal Stromal Tumor Syndrome - ASCO ...

A germline KIT exon 11 T → C missense mutation, resulting in a V559A juxtamembrane domain substitution, was found in the proband, ...

#71. Tyrosinkinase KIT - DocCheck Flexikon

Die Tyrosinkinase KIT, kurz KIT, ist eine Rezeptortyrosinkinase, die vor allem von hämatopoetischen Stammzellen (HSCs) und Mastzellen exprimiert wird.

#72. c-KIT - 转化医学网

基因功能cKIT（v-kit Hardy-Zuckerman 4 feline sarcoma viral oncogene homolog）属于原癌基因C-kit编码的III型受体酪氨酸激酶家族成员。C-kit基因编码的kit蛋白由胞 ...

#73. Антиген CD117 (c-kit) - Beckman Coulter

Антиген CD117 (c-kit). Антиген CD117, также известный как рецептор фактора роста стволовых клеток (SCFR) и тучных клеток (mast-cell-Kit) и рецептор ...

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小管線泄漏修補組Kit C-2. 商品編號：Edwards & Cromwell Kit C-2 ... 18”X22”EXTRA FOAM; 8”X12”EXTRA RUBBER; TOOL PACK; CARRYING CASE; TOOL PACK NON SPARKING.

#76. Molecular Mechanisms of Adult Stem Cell Aging

Lin–c-Kit+Sca1+Flk2–CD34–Slamf1+ Lin–CD34+CD38–CD90+CD45RA+ Lin – c-Kit+Sca1+Flk2 – CD34+Slamf1+ Lin–CD34+CD38–CD90–CD45RA– Lin–c-Kit+Sca1 +Flk2+CD34+Slamf1 ...

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C by GE smart bulbs let you turn on the lights with your voice. The smart lights starter kit comes with C by GE Tunable C-Sleep Smart Bulb 2‑Pack and a ...

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C++ 可轉散發套件安裝Microsoft C 和c + + (MSVC) 執行時間程式庫。 ... Visual Studio 2010 Service Pack 1 已達2020年7月14日的延伸支援結束 ...

#80. Arduino - Home

Open-source electronic prototyping platform enabling users to create interactive electronic objects.

#81. c-kit遺伝子変異検査 - ケーナインラボ

c -kit遺伝子変異検査. はじめに. 近年、犬および猫の肥満細胞腫においては、チロシンキナーゼ阻害剤（TKI：Tyrosine ...

#82. PNAS：C-KIT的新功能及其医学转化意义 - 生物通

但是，C-KIT赋予癌细胞逃逸凋亡的机制仍不清楚，如何针对C-KIT开展有效的靶向疗法也亟需进一步研究。日前，《美国国家科学院院刊》（Proceedings of the ...

#83. GIST関連用語集c-kit遺伝子 - がんを学ぶ

GIST（消化管間質腫瘍）関連用語集です。「c-kit遺伝子」はKITたんぱくの設計図にあたる遺伝子のこと。c-kit遺伝子が突然変異し異常なKITたんぱくが作られ、細胞が異常 ...

#84. KIT (CD117): A Review on Expression in Normal and ...

28. Hirota S, Isozaki K, Moriyama Y, et al. Gain-of-function mutations of c-kit in human gastrointestinal stromal tumors.

#85. VMware - Delivering a Digital Foundation For Businesses

Run any app on any cloud on any device with a digital foundation built on VMware solutions for modern apps, multi-cloud, digital workspace, ...

#86. Illumina | Sequencing and array-based solutions for genetic ...

Compare and cart products. Find the Right Kit. Popular Tools. MyIllumina Customer Dashboard. Sign In or Learn More. Library Prep and Array Kit Selector.

#87. PyroGene™ Recombinant Factor C Assay - Lonza Bioscience

PyroGene TM Recombinant Factor C Endpoint Fluorescent Assay. 2 × 96 tests/vial rFC enzyme solution, 2 × 6 mL vial fluorogenic substrate, 2 × 5 mL vial rFC ...

#88. Java Downloads | Oracle

Java SE Development Kit 17.0.1 downloads. Thank you for downloading this release of the Java™ Platform, Standard Edition Development Kit (JDK™). The JDK is a ...

#89. Systemic Mastocytosis Medication - Medscape Reference

Avapritinib is a tyrosine kinase inhibitor that binds to and inhibits specific mutant forms of PDGFRα and c-Kit, including the PDGFRα D842V ...

#90. List of Drugs being provided in ASHA Kit - National Health ...

ASHA is provided with a drug kit containing a set of drugs/equipment and products that enable her to provide basic level care and enhance ...

#91. Tyrosine kinase inhibitors reverse type 1 diabetes in ... - PNAS

In addition, imatinib has been found to be active against other tyrosine kinases such as platelet-derived growth factor receptor (PDGFR), c-Kit ...

#92. KIT - Startseite

Willkommen im Studierendenportal des KIT. Hallo Gast!Anmelden. Das Campus Management Portal bietet den Studierenden des KIT verschiedene Services zur ...

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#94. NCR+ ILC3 Cell Markers - R&D Systems

(B) CD117 + CD127 + ILCs in the lineage negative population were detected by staining with an APC-conjugated Rat Anti-Mouse CD117/c-kit Monoclonal Antibody (R&D ...

#95. What does c-kit mean? Definition, meaning and sense

C -kit. A protein found on the surface of many different types of cells. It binds to a substance called stem cell factor (SCF), which causes certain types of ...

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#97. PDGFRA Immunohistochemistry Predicts PDGFRA Mutations ...

C and D, PDGFRA IHC is positive at 1:3000 and 1:10,000 dilutions, respectively. PDGFRA was positive in all 4 PDGFRA-mutant GISTs that were negative for KIT ...