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#11. Polyadenylation (or Poly(A)) signal, site and tail - IMGT ...

The sequence elements for polyadenylation include the polyadenylation signal (POLYA_SIGNAL) and the polyadenylation site (POLYA_SITE). In mRNA ...

#12. Cytoplasmic Polyadenylation in Development and Beyond

SUMMARY Maternal mRNA translation is regulated in large part by cytoplasmic polyadenylation. This process, which occurs in both vertebrates ...

#13. Polyadenylation - NEJM Illustrated Glossary

The sequential addition of adenine bases to the 3′ end of pre–messenger RNA (pre-mRNA), thus forming a poly(A) tail. Polyadenylation is part of the maturation ...

#14. PolyASite 2.0: a consolidated atlas of polyadenylation sites ...

Abstract. Generated by 3′ end cleavage and polyadenylation at alternative polyadenylation (poly(A)) sites, alternative terminal exons ...

#15. Comprehensive Polyadenylation Site Maps in Yeast and ...

Here, we report comprehensive maps of global polyadenylation events in human and yeast generated using refinements to the Direct RNA Sequencing ...

#16. RNA polyadenylation and its consequences in prokaryotes

Polyadenylation refers to an enzymatic process carried out by poly(A) polymerase to add adenine residues to the 3′ extremity of RNAs.

#17. Different types of alternative polyadenylation and their possible...

A complex interaction between the cleavage and polyadenylation molecular complex and cis-elements determine the polyadenylation site, which may result in the ...

#18. Polyadenylation of Sine Transcripts Generated by RNA ...

The transcripts of some mammalian SINEs have an ability to undergo AAUAAA-dependent polyadenylation, which is unique for the RNA polymerase ...

#19. The Pattern of Alternative Polyadenylation | Plantae

Polyadenylation requires poly(A) signal recognition, cleavage, and addition of the A nucleotides. At least 50% of genes in humans, animals, ...

#20. Role of Arginine Methylation in Alternative Polyadenylation of ...

Mature mRNA is generated by the 3ʹ end cleavage and polyadenylation of its precursor pre-mRNA. Eukaryotic genes frequently have multiple polyadenylation ...

#21. A dynamic interplay between alternative polyadenylation and ...

Alternative polyadenylation and microRNA regulation are both mechanisms of post-transcriptional regulation of gene expression.

#22. Mechanisms of mRNA polyadenylation - DergiPark

All eukaryotic pre-mRNAs undergo polyadenylation, i.e. cleavage and polyadenylation at the 3' untranslated region (UTR), except replication-dependent histone ...

#23. Alternative Polyadenylation(APA) modulates extracellular ...

Alternative Polyadenylation(APA) modulates extracellular matrix deposition in pulmonary hypertension. S Collum, T Weng, A Hernandez, T Mertens, N Chen, ...

#24. Martinson - Cleavage and Polyadenylation

Cleavage and polyadenylation is directed by a poly(A) signal in the RNA. The core poly(A) signal for vertebrate pre-mRNAs consists of two recognition ...

#25. DeepPolyA: A Convolutional Neural Network Approach for ...

Polyadenylation (Poly(A)) plays crucial roles in gene regulation, especially in messenger RNA metabolism, protein diversification, ...

#26. Alternative polyadenylation and the stress response - Sadek

RNA Processing > 3′ End Processing. Abstract. Various stresses induce alternative polyadenylation of nascent transcripts modulating their ...

#27. Comprehensive characterization of alternative ...

Background: Alternative polyadenylation (APA) is emerging as a major post-transcriptional mechanism for gene regulation, and dysregulation ...

#28. Protein 1 of cleavage and polyadenylation factor 1 - Society ...

Pol II termination is coupled to polyadenylation by the polyadenylation signal in the nascent transcript. Two models have been proposed to ...

#29. Alternative mRNA Cleavage and Polyadenylation in Genetic ...

#30. Laminar Shear Stress and 3′ Polyadenylation of eNOS mRNA

The 3′ poly(A) tail is important in messenger RNA stability and translational efficiency. In somatic tissues, 3′ polyadenylation of mRNAs ...

#31. PolyA_DB -- A database for mammalian mRNA polyadenylation

The database provides several types of information regarding polyadenylation in mammalian species: (i) polyadenylation sites and their ...

#32. Polyadenylation of mRNA in bacteria | Microbiology Society

This review presents the accumulated evidence for the extensive 3′-polyadenylation of bacterial mRNA and for a complex enzymic machinery that ...

#33. Alternative polyadenylation of single cells delineates ... - PLOS

Alternative polyadenylation (APA) in 3' untranslated regions (3' UTR) plays an important role in regulating transcript abundance, ...

#34. RNA-seq Quantification of Alternative Polyadenylation (QAPA)

Analysis of alternative polyadenylation (APA) from RNA-seq data (human and mouse). QAPA consists of two main components: Extraction and annotation of 3′ UTR ...

#35. WikiGenes - Polyadenylation - Evolutionary Knowledge

Uridylate-containing RNA sequences determine specificity for binding and polyadenylation by the catalytic subunit of vaccinia virus poly(A) polymerase [4]. We ...

#36. PolyA-miner accurately assesses the effect of alternative ...

PolyA-miner enables scientists to evaluate the contribution of alternative polyadenylation to gene regulation in health and disease.

#37. Functional Interaction of BRCA1-Associated BARD1 ... - Science

Polyadenylation of messenger RNA precursors requires a complex protein machinery that is closely integrated with the even more complex transcriptional ...

#38. Cytoplasmic polyadenylation-mediated translational control of ...

Cytoplasmic polyadenylation-mediated translational control of maternal mRNAs directs maternal-to-zygotic transition · In the earliest stages of animal ...

#39. Polyadenylation Regulates the Stability of Trypanosoma ...

The role of polyadenylation in the turnover of mitochondrial RNAs is not well ... but polyadenylation of mature mRNA 3′-ends is correlated with reduced RNA ...

#40. cpsf-3 - Cleavage and Polyadenylation Specificity Factor

mRNA cleavage and polyadenylation specificity factor complex, 5'-3' exonuclease activity, endoribonuclease activity, RNA binding, mRNA 3'-end processing by ...

#41. Strange bedfellows: polyadenylation factors at the promoter

TFIID, RNA polymerase II, and the polyadenylation machinery. The story began back in 1997 with the discovery that the general transcription factor (GTF) ...

#42. The impact of cytoplasmic polyadenylation on local translation ...

In neurons, cytoplasmic polyadenylation of synaptic mRNAs plays a significant role in the regulation of protein synthesis. However, until now it was studied ...

#43. Polyadenylation - SlideShare

3. Polyadenylation is the addition of a poly(A) tail to a messenger RNA. The poly(A) tail consists of multiple adenosine monophosphates; in other ...

#44. Alternative Polyadenylation in Human Diseases - Semantic ...

Varying length of messenger RNA (mRNA) 3′-untranslated region is generated by alternating the usage of polyadenylation sites during pre-mRNA ...

#45. definition of polyadenylation by Medical dictionary

polyadenylation. addition of a sequence of ADENINE NUCLEOTIDES to the 3′-end of most eukaryotic RNA molecules, after their TRANSCRIPTION. The sequence is often ...

#46. Cleavage and polyadenylation of Intronless Pre-mRNA

Cleavage and polyadenylation of Intronless Pre-mRNA. Stable Identifier. R-MMU-77593. Type. Reaction [dissociation]. Species. Mus musculus. Compartment.

#47. Cleavage and polyadenylation of pre-mRNA - Malaria ...

PFID PFID Old Annotation PF3D7_0109200 PFA0450c CFI PF3D7_0403700 PFD0180c CFI PF3D7_1420000 PF14_0194 CFI

#48. RNA-Based Regulation in Human Health and Disease

Polyadenylation begins after a readthrough of a polyadenylation signal of “AAUAAA” [37]. A large complex is formed around this signal site and w15 bases ...

#49. Lecture 8.4 Capping and Polyadenylation - FLAX library

Here's a schematic of how polyadenylation occurs on a DNA template for most viruses except Poxviruses. We have, the top here is a mRNA in the process of being ...

#50. Lewin's Cells - 第 137 頁 - Google 圖書結果

In most cases, additional polyadenylation enhancer elements are located upstream and downstream of the cleavage site. (b) The poly(A) signal in yeast is ...

#51. Polyadenylation - WIKI 2

1 Background on RNA · 2 Nuclear polyadenylation. 2.1 Function; 2.2 Mechanism; 2.3 Downstream effects; 2.4 Deadenylation; 2.5 Alternative ...

#52. Polyadenylation – the process | The RNA Underworld

While the process of polyadenylation seems simple enough, it actually involves a rather large number of proteins (more than 20, if one counts ...

#53. RNA Biochemistry and Biotechnology - 第 262 頁 - Google 圖書結果

Polyadenylation Retroviruses with an extended R region encode the polyadenylation ( polyA ) signal within the R region , such that it is present at both the ...

#54. 3'-end Cleavage and Polyadenylation.

In eukaryotes, polyadenylation is part of the process that produces mature messenger RNA (mRNA) for translation. It, therefore, forms part of ...

#55. Molecular Biology and Genetic Engineering

Polyadenylation and the generation of 3 ' end in eukaryotes The 3 ' end of mRNA is generated in two steps ( Fig . cap Poly ( A ) 13.2 ) ( i ) Nuclease ...

#56. polyAdb - compbio.dundee.ac.uk

polyADB gives you information about, and access to, large polyadenylation-related datasets by providing ready-to-go, pre-processed, downloadable files in a ...

#57. BIOS Instant Notes in Biochemistry - 第 225 頁 - Google 圖書結果

3 processing: cleavage and polyadenylation snRNPs (see above), and since these sequences are different in the minor intron class, U1, U2, U4, ...

#58. RNA-Protein Interaction Protocols[ - 第 448 頁 - Google 圖書結果

Sallés, F. J. and Strickland, S. (1995) Rapid and sensitive analysis of mRNA polyadenylation states by PCR. PCR Methods Appl. 4, 317–321. 2.

#59. Cell and Molecular Biology of Plastids - 第 185 頁 - Google 圖書結果

3.1 Historical perspective on polyadenylation Polyadenylation is an important posttranscriptional modification of prokaryotic, eukaryotic and organellar RNA ...

#60. A series of BRAF- and NRAS-driven murine melanoma cell ...

... cell lines (M175M1 and M175M2) underwent an aberrant recombination reaction where the three SV40 polyadenylation signals and the 3' loxP ...

#61. Mmlv promoter - Whereat - Risto

Also facilitates transcription termination and mRNA polyadenylation in ES cells and other cell types. 1-Hygro-JY4-3XFlagN-GS3 vector ...

#62. Splicing lab - Medical Supply

... Our lab and others have shown that these three processes, transcription, splicing and polyadenylation, are all linked, or coupled, in interesting ways.

#63. The Dictionary of Cell and Molecular Biology

polyadenylation. distantly related, are usually heterodimers or multimers with a high and a low affinity component and signal through JAKs.

#64. Cumulated Index Medicus

Arerugi 1994 Jul ; 43 ( 7 ) : 800-8 ( Eng . common erythroid - specific promoter and alternative usage Abstr . ) ( Jpn ) of different polyadenylation ...

#65. VMC 211: General Veterinary Microbiology (1+1) - Course

Capping & Polyadenylation Page · Genome replication Page · Assembly and release Page · PODCAST File · Quiz. Topic 20. Click here... Viral genetics.

#66. Mesv promoter

The LTRs carry both promoter and polyadenylation function, such that the 5' LTR acts as a promoter to drive the transcription of the viral genome, ...

#67. Biology test 1 answers - Golf Refugees

ANSWERS TO BIOLOGY TEST 2 Answers to Biology Test Part I Question 1 (a) during polyadenylation, what is the pre-mRNA sequence's function corresponding to ...

#68. Protein sequence classification kaggle

... Atlas Image Classification. pep) ssRNA classification of viruses) about 30 kb in length that has a 5′ cap structure and 3′ polyadenylation tract.

#69. Joseph Heimiller - Bioinformatics Research Scientist - LinkedIn

The loss of FUS leads to RNAP2 accumulation at the transcription start site and a shift in mRNA isoform expression toward early polyadenylation sites.

#70. Mmlv promoter

Also facilitates transcription termination and mRNA polyadenylation in ES cells and other cell types. T7 RNA polymerase produces multiple copies of RNA ...