關於 pgi2 receptor ，我們在網路上蒐集到這些相關的討論、資訊與評價

#11. Prostaglandin I2 Receptor Polyclonal Antibody - Thermo Fisher

Protein Aliases: IP receptor; PGI receptor; PGI2 receptor; Prostacyclin receptor; prostaglandin I receptor (IP); Prostaglandin I2 receptor; Prostanoid IP ...

#12. Anti-Prostacyclin Receptor (PTGIR) (extracellular) Antibody

Anti-Prostacyclin Receptor (PTGIR) (extracellular) Antibody. Prostanoid IP receptor, Prostaglandin I2 receptor, PGI2 receptor. In Stock.

#13. Increased role of E prostanoid receptor-3 in prostacyclin - Nature

These results thus demonstrate an explicit involvement of EP3 in PGI2- evoked vasoconstrictor activity in rat mesenteric resistance arteries and suggest that up ...

#14. Prostacyclin receptor | DrugBank Online

PGI receptor; PGI2 receptor; PRIPR; Prostaglandin I2 receptor ... adenylate cyclase-activating G-protein coupled receptor signaling pathway / blood ...

#15. Platelet PGI2 receptor affinity is reduced in pre-eclampsia.

Prostacyclin (PGI2) receptors were studied in platelet membrane preparations from women with normal pregnancy, pregnancy-induced hypertension (PIH) or ...

#16. PGI2 (IP) - Prostanoid - GPCR - Receptors - Axon Medchem

PGI2 (IP). The Prostacyclin (PGI2) receptor , also termed the prostaglandin I2 receptor or just IP, is coupled to a guanosine nucleotide-binding ...

#17. compositions comprising pgi2-receptor agonists and ...

Provided herein in some embodiments are pharmaceutical compositions comprising a prostacyclin (PGI2) receptor agonist selected from 2-(((1r ...

#18. Prostaglandin I2 (prostacyclin) receptor (IP) (IP1) - DiscoverX

... PGI2 receptor; PRIPR; prostacyclin receptor; prostaglandin I2 (prostacyclin) receptor (IP); prostaglandin I2 receptor; prostanoid IP receptor ...

#19. A Novel Pathway of Prostacyclin Signaling—Hanging Out with ...

actions involving both cell surface and nuclear receptors. Al- though the signaling of PGI2 via its cell surface receptor, pros- tacyclin receptor (IP) ...

#20. Effect of Prostanoids on Human Platelet Function - MDPI

In human platelets, it can bind to IP—the PGI2 receptor—as well as to PGE receptors [162]. In mice, the rank order of affinity is EP3 > EP4 > ...

#21. Evidence for distinct prostaglandin I2 and D2 receptors in ...

Studies of agonist-specific desensitization of cAMP accumulation show that PGE1 or PGE2 can desensitize for subsequent PGE or PGI2 activation, ...

#22. Prostaglandin I2 Receptor (PTGIR, IP Receptor, PGI ... - BIOZOL

Prostaglandin I2 Receptor (PTGIR, IP Receptor, PGI Receptor, PRIPR, Prostaglandin I2 Receptor, IP, PGI2 Receptor, Prostacyclin IP Receptor, ...

#23. KR20190124261A - Compositions comprising PGI2-receptor ...

Compositions comprising PGI2-receptor agonists and methods of making the same ... Binding of PGI2 (or other such agonists) to PGI2 receptors is known to ...

#24. ptgir

PTGIR Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.

#25. Prostacyclin-mediated activation of peroxisome ... - PNAS

previous study suggested that PGI2 was not signaling through the G protein-coupled prostacyclin (IP) receptor, but rather through activation of PPAR.

#26. PGI2 ELISA Kits - Biocompare

Listed are ELISA Kits for the detection of PGI2, an alias name of prostaglandin I2 receptor. The human protein, encoded by the gene PTGIR, ...

#27. IP receptor (pi2r_human) - GPCRdb

Class A (Rhodopsin) Lipid receptors Prostanoid receptors IP receptor ... Prostacyclin receptor, Prostaglandin I2 receptor, PGI receptor, PGI2 receptor, ...

#28. Human Prostacyclin (PGI2) ELISA Kit - MyBioSource

Prostacyclin receptor. UniProt Synonym Protein Names. Prostaglandin I2 receptor; PGI receptor; PGI2 receptor; Prostanoid IP receptor. Protein Family.

#29. Eicosanoid biosynthesis and action: novel opportunities for ...

for a prostacyclin mimetic can be achieved only if PGI2 receptors on vascular smooth muscle cells are different from those on platelets. Until recently, no ...

#30. Insights from the Prostacyclin (PGI2) Receptor Agonist in ...

... the Prostacyclin (PGI2) Receptor Agonist in Pulmonary Arterial ... enrolled in the Prostacyclin (PGI2) Receptor Agonist in Pulmonary ...

#31. IP receptor - IUPHAR/BPS Guide to PHARMACOLOGY

IP receptor - Prostanoid receptors. Detailed annotation on the structure, function, physiology, pharmacology and clinical relevance of drug targets.

#32. Showing Compound Prostaglandin I2 (FDB022560) - FooDB

The platelet Gs protein-coupled receptor (prostacyclin receptor) is ... PGI2 also binds to endothelial prostacyclin receptors and in the ...

#33. Prostanoids and isoprostanoids in atherogenesis - Abcam

Their vascular effects are mediated by specific G-protein coupled prostanoids receptors called TP receptors and IP receptor, respectively. TxA2 and PGI2 are ...

#34. Pgi2 | Sigma-Aldrich

Find pgi2 and related products for scientific research at Merck. ... of PGE2 and PGI2 in HUVEC via the angiotensin AT1 receptor and ...

#35. Estradiol selectively stimulates endothelial prostacyclin ...

The role of different estrogen receptors (ERs) in the PGI2/TXA2 balance, ... Estrogen receptor-α and estrogen receptor-β protein expression in HUVECs.

#36. PGI2 [extracellular region] - Reactome

PGI2 [extracellular region] · Activated prostacyclin receptor binds G-protein Gs (Homo sapiens). PTGIR:PGI2 [plasma membrane] (Homo sapiens) · Dissociation of the ...

#37. anti-IP Receptor antibody (ARG56490) - arigo Biolaboratories

Alternate Names, PRIPR; Prostaglandin I2 receptor; IP; Prostacyclin receptor; Prostanoid IP receptor; PGI2 receptor; PGI receptor ...

#38. Prostaglandin I2 (PGI2) inhibits Brucella abortus ... - X-MOL

To date, the implications of prostaglandin I2 (PGI2), a prominent ... and PGI2 receptor (PTGIR) expression was downregulated in BMMs but ...

#39. Prostaglandin I2 Receptor Antibody – Bioss

Cyclooxygenases metabolize arachidonate to five primary prostanoids: PGE2, PGF2?, PGI2, TXA2 and PGD2. These lipid mediators interact with specific members of G ...

#40. The Unique Ligand-binding Pocket for the Human ...

tacyclin and its receptor, have yet to be determined. As is the case with all prostanoids, prostacyclin (PGI2) is a derivative of the C20 unsaturated fatty ...

#41. Pharmacology of Smooth Muscle - 第 137 頁 - Google 圖書結果

There is little information on PGE receptors in vascular smooth muscle, ... A PGI2 receptor was recently characterized in membranes of mastocytoma cells by ...

#42. Medline ® Abstract for Reference 2 of 'NSAIDs: Adverse ...

Here we show that injury-induced vascular proliferation and platelet activation are enhanced in mice that are genetically deficient in the PGI2 receptor ...

#43. Naoto OHKURA - Papers - researchmap

Orthodontic force application upregulated pain-associated prostaglandin-I2/PGI2-receptor/TRPV1 pathway-related gene expression in rat molars. Odontology.

#44. Localization of the prostacyclin receptor in human ... - CORE

Northern analysis showed highest expression of IP receptor. mRNA in kidney, arguing for an important role of prosta- cyclin in renal physiology. PGI2 ...

#45. Prostacyclin Receptor-dependent Modulation of Pulmonary ...

tients with severe pulmonary hypertension have a reduced PGI2 receptor (PGI-R) expression in the remodeled pulmonary arterial smooth muscle, we hypothesized ...

#46. DeCS Server - List Exact Term

Synonyms English: Epoprostenol Receptors PGI2 Receptor PGI2 Receptors Prostacyclin Receptor Prostacyclin Receptors Prostaglandin I2 Receptor Prostaglandin I2 ...

#47. Textbook of Pulmonary Vascular Disease - 第 701 頁 - Google 圖書結果

Specific ETA receptor antagonism in rats has been shown to decrease the PH, ... The PGI2 receptor (PGI-R) is a member of the G-protein-coupled-receptor ...

#48. Prostacyclin Receptor Regulation --- from Transcription to ...

Endothelial PGI2 binds to the Gs-coupled PGI2 receptor on platelets, thereby reducing platelet reactivity, which can be critical to ...

#49. Activation of the PGI2/IP System Contributes to ... - AHA Journals

Here, we examine the specific role of prostacyclin and of the receptor for prostacyclin (IP) ... lar smooth muscle cells (VSMCs).1 Stimulation of IP by PGI2.

#50. Demonstration of a Novel Circulating Anti-Prostacyclin ... - jstor

PGI2 receptor, demonstrates that the specific recognition and inhibition of high-affinity PGI2 binding to platelets was due to an anti-prostacyclin receptor ...

#51. Prostaglandin Receptor antagonist - Selleckchem.com

RO1138452 (CAY10441) is a potent and selective antagonist of IP (prostacyclin, PGI2) receptor with pKi of 9.3 and 8.7 in human platelets and a recombinant IP ...

#52. Showing Protein Prostacyclin receptor (HMDBP02751)

PGI receptor; PGI2 receptor; Prostaglandin I2 receptor; Prostanoid IP receptor. Gene Name, PTGIR. Protein Type, Enzyme. Biological Properties.

#53. New Insights into the Intracellular Mechanisms by Which PGI2 ...

Prostaglandin I2 (PGI2, prostacyclin), an eicosanoid of the cyclooxygenase ... PGI2 and its stable analogues activate a specific cell-surface receptor (IP ...

#54. ProstaglandinI2參與大白鼠孤獨核調控感壓反射之研究

Besides, previous studies evidenced that cyclooxygenase (COX) and PGI2 receptor are located in NTS. However, the physiological role of PGI2 in NTS is still ...

#55. Signaling through the PGI 2 Receptor Promotes IL-17 ...

Signaling through the PGI2 Receptor Promotes IL-17 Production by CD4 T Cells ... we determined the effect of PGI2 and PGI2 receptor (IP) signaling on IL-17 ...

#56. 國立成功大學機構典藏

Other Titles: Study of the prostaglandin receptors in ... PGD2 PGI2 and TXA2 Selective COX-2 inhibitors such as NS-398 have been reported to ...

#57. Human and Rodent Prostaglandin Receptors & Prostacyclin ...

PGI2 and PGE2 exert their biologic actions by binding to their respective receptors, namely prostacyclin receptor (IP) and prostaglandin E2 ...

#58. Localization of the prostacyclin receptor in human kidney

In human kidney sections both IP receptor-immunoreactive protein and mRNA were ... Characterization of the PGE2 receptor subtypes and PGI2 receptor in the ...

#59. Prostanoid receptor expression in colorectal cancer related to ...

additional receptor expression (DP1, DP2, FP, IP, TP) for prostanoids (PGD2, TXA2, PGF2a, PGI2) in relationship to tumor stage, differentiation and ...

#60. Prostaglandin I2 signaling licenses Treg suppressive function ...

allergic inflammation; however, the effect of PGI2 on Treg function was not investigated. Tregs from mice deficient in the PGI2 receptor IP ...

#61. Targeting the Prostacyclin Pathway: Beyond Pulmonary ...

of more stable and more selective drugs that target the PGI2 receptor (IP receptor) in PAH has led to the recent development of non-prostanoid IP agonists ...

#62. Brenner and Rector's The Kidney E-Book - 第 369 頁 - Google 圖書結果

Most evidence suggests that the PGI2 receptor signals via stimulation of cAMP generation; however, at 1000-fold higher concentrations, the cloned mouse PGI2 ...

#63. Carbacyclin (Synonyms: Carbaprostacyclin; Carba-PGI2)

Carbacyclin is a PGI2 analogue, acts as a prostacyclin (PGI2) receptor agonist and vasodilator, and potently inhibits platelet aggregation.

#64. Prostacyclin signaling in the kidney: implications for health ...

nized receptors that mediate the effects of PGI2, the cell- surface IP receptor and the nuclear peroxisome proliferator- activated receptor δ (PPARδ).

#65. Prostacyclin Receptor Antibody [102-15895] - RayBiotech

Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.

#66. 3D-QSAR models for PGI2 receptor ligands Local intersection ...

The models obtained can be applied to design new PGI2 receptor ligands with potential platelet anti-aggregating activity. 3D-QSAR; local intersection volume ...

#67. Synthetic Prostacyclin Analogs Differentially Regulate ...

Given this ability to stimulate cAMP production through the IP receptor, we hypothesized that PGI2 analogs might inhibit pulmonary innate ...

#68. Temporary treatment interruptions with oral selexipag in ...

Temporary treatment interruptions with oral selexipag in pulmonary arterial hypertension: Insights from the Prostacyclin (PGI2) Receptor Agonist in ...

#69. Anti-Prostaglandin I2 Receptor/APC - Biorbyt

Catalog Number: orb991999 ; Human · APC · KLH conjugated synthetic peptide derived from human Prostaglandin I2 Receptor · (click to expand) IP; PGI receptor; PGI2 ...

#70. receptor/TRPV1 pathway-related gene expression in rat molars

This study aimed to analyze the mRNA expression and protein localization of prostaglandin I2 (PGI2) synthase (PGIS), the PGI2 receptor (IP ...

#71. Molecular Aspects of Pathophysiology of Platelet Receptors

The PG receptors, especially PGE2 and PGI2, bear a pivotal responsibility in platelet aggregation phenomena to maintain hemostasis, as mentioned earlier.

#72. PGI2 Inhibits Intestinal Epithelial Permeability and Apoptosis ...

epithelial cell; IFN, interferon; IL, interleukin; IP, prostaglandin. I2 receptor; MLC, myosin light chain; PBS, phosphate-buffered saline;.

#73. Distribution and Cellular Localization of Prostacyclin Synthase ...

Prostacyclin (PGI2) is a labile, lipid-derived metabolite of arachidonic acid syn- ... are mediated by specific cell surface receptors called IP.

#74. Actelion's PGI2 receptor agonist demonstrates efficacy in ...

Actelion's PGI2 receptor agonist demonstrates efficacy in pulmonary arterial hypertension patients - Morbidity-Mortality Phase III study to ...

#75. channels mediate relaxation by the PGI2 receptor agonist ...

receptor agonist cicaprost via a cyclic AMP-independent mechanism. Nelson N. Orie ... selectivity for the PGI2 receptor (IP receptor), research has.

#76. IP Receptor (mouse) Blocking Peptide - Cayman Chemical

IP Receptor (mouse) Blocking Peptide - 1 each - CAY360070-1 ea from Cayman Chemical. ... pgi2 receptor, prostacyclin receptor, prostaglandin i2 receptor.

#77. Prostacyclin in Vascular Diseases - J-Stage

These actions of PGI2 are mediated through specific cell surface receptors, known as IP. IP is a 7-membrane spanning. G-protein coupled receptor that ...

#78. Beraprost sodium, a prostacyclin (PGI) analogue, ameliorates ...

The PGI2 receptor is expressed in alveolar epithelial cells (21), but the effects of beraprost on inflammation and.

#79. Recent advances in targeting the prostacyclin pathway in ...

Selective non-prostanoid. IP receptor agonists. FIGURE 1 Involvement of the endothelin, nitric oxide and prostacyclin (PGI2) pathways in the pathogenesis of.

#80. Acute reversible reduction of PGI2 platelet receptors after ...

Platelet sensitivity to PGI2 and platelet PGI2 receptors were investigated in eight subjects with peripheral artery disease (stage IV according to Fontaine) ...

#81. The COX-2/PGI2 Receptor Axis Plays an Obligatory Role in ...

These results provide unequivocal molecular genetic evidence for an essential role of the COX-2/PGI2 receptor axis in the cardioprotection afforded by the ...

#82. anti-Prostacyclin Receptor antibody (Internal Region)

Target Details for Prostacyclin Receptor (hide). Target: Prostacyclin Receptor (PTGIR); Alternative Name: PTGIR (PTGIR Products); Synonyms: IP, PGI2, PRIPR, ...

#83. Team studies new use for pulmonary hypertension drug

Mice missing the PGI2 receptor had increased allergic airway inflammation, but surprisingly, they had increased numbers of T regulatory ...

#84. (5Z)-carbacyclin discriminates between prostacyclin - AIR Unimi

We conclude that the receptors for PGI2 coupled to adenylate cyclase in platelets and vascular ... degree of selectivity for the platelet receptor will be.

#85. Role of prostanoid IP and EP receptors in mediating ...

Semantic Scholar extracted view of "Role of prostanoid IP and EP receptors in mediating vasorelaxant responses to PGI2 analogues in rat tail ...

#86. PTGIR Protein - Creative BioMart

Synonyms, PTGIR; prostaglandin I2 (prostacyclin) receptor (IP); prostacyclin receptor; IP; PGI receptor; PGI2 receptor; prostanoid IP receptor; ...

#87. Retinoic acid induces PGI synthase expression in human ...

retinoic acid receptor • cyclooxygenase pathway. In the vascular tissue, prostaglandin I2 (PGI2, also called prostacyclin) is mainly produced by endothelial ...

#88. Recombinant Mouse Prostacyclin receptor(Ptgir),partial

Uniprot No. P43252. Alternative Names, Ptgir; Prostacyclin receptor; Prostaglandin I2 receptor; PGI receptor; PGI2 receptor; Prostanoid IP receptor. Species ...

#89. PGI2 IP receptor role in global ischemia in young and aged mice

PGI2 IP receptor role in global ischemia in young and aged mice. Saleem, Sofiyan (PI). Internal Medicine, Phoenix. Project: Research project.

#90. Molecular mechanisms underlying the actions of arachidonic ...

receptor-specific actions of PGs mostly heighten neuronal excitability, which can cause pro-nociceptive outcomes. ... The PGI2 receptor (IP) in nociceptors.

#91. Prostaglandin EP2 receptor: Novel therapeutic target for ...

The following standard prostaglandins can activate EP2, with a binding efficacy in the following order: PGE2>PGF2α≥PGI2>PGD2 (100). Receptor- ...

#92. Prostaglandins (PGs) and Thromboxanes (TXs) - SlidePlayer

PHRM 4050 Fall 2011 PGI2 vs TXA2 (Mechanism) PGI2 TXA2 Prostaglandin I2 receptor (IP2) GPCR cAMP signaling pathway PPAR nuclear receptor ...

#93. 杉本教授研究内容 - SQUARE

... は、4種類のプロスタグランジンPGE2、PGD2、PGF2α、PGI2とトロンボキセンA2で ... D Prostanoid receptorという意味でDP、同様にPGE2、PGF2α、PGI2、TXA2の受容体 ...

#94. 急性心衰和心源性休克课件.ppt - 人人文库网

... NE, AngII, TxA2, vasopressinvasodilators: PGI2, NO, adenosine, ... 34、ases NE releaseMultiple receptor affinities depending on ...

#95. Top 12 Prostacyclin Là Gì - Tài Chính Kinh Doanh

... như: Pgi2 là gì, Prostaglandin là gì, Prostaglandin I2 là gì, ... Khớp với kết quả tìm kiếm: -TPα ᴠà TPβ receptor qua Gq hoạt hóa lộ ...

#96. 017 Two Types of Receptors - YouTube

http://www.interactive-biology.com - In this video I talk about the two types of receptors - the ionotropic and metabotropic receptors and ...

#97. Prostaciclina FunciónyUsos médicos

El receptor acoplado a proteína G de plaquetas (receptor de prostaciclina ) se ... La PGI2, derivada principalmente de la COX-2 en humanos, es el principal ...