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#1. A practical guide on how to handle patients with bleeding ...
由 ME Gimbel 著作 · 2018 · 被引用 21 次 — The ESC DAPT guideline recommends interrupting DAPT and switch to single antiplatelet therapy, preferably the P2Y12 inhibitor, especially in ...
#2. 2018 Expert Consensus on the Management of Adverse ...
gest that the use of dual antiplatelet therapy (DAPT) with potent antiplatelet agents in ACS can ... of GI bleeding among DAPT with ticagrelor vs. clopido-.
#3. Is There an Optimal Antiplatelet Strategy after Gastrointestinal ...
Nomogram for bleeding risk calculation with PRECISE DAPT [18]. ... In the case of the above patient who had a GI bleed 1 year after a newer generation DES for an ...
#4. Bleeding on dual antiplatelet therapy: real-life challenges
GI bleeding of DAPT is an important issue especially in the first 3 months as interruption of DAPT during this period may increase chances ...
#5. The challenge of nonvariceal upper GI bleeding management ...
further increases the risk of GI bleeding.2. Dual antiplatelet therapy (DAPT) is a combination treatment with aspirin and a P2Y12 inhibitor.
#6. Management of antiplatelet agents in patients undergoing ...
○If bleeding risk from an endoscopic procedure is low, DAPT is continued ... bleeding — For patients with life-threatening GI bleeding, ...
#7. Endoscopy study reveals GI injury after DAPT - Nature
In total, 505 patients who had undergone 6 months of DAPT after PCI and were free from GI tract ulceration or bleeding were randomly ...
#8. OPT-PEACE: Antiplatelet Therapy Regimens and GI Injury in ...
In other findings, lower rates of gastrointestinal bleeding were observed between six and 12 months with SAPT compared with DAPT (0.6% vs.
#9. Clinical Impact of Gastrointestinal Bleeding in Patients ...
10 Although prolonged. (12 months) duration of dual antiplatelet therapy (DAPT) is the current standard of care after PCI with drug-eluting stents. (DES),15 the ...
#10. Reducing Gastrointestinal Bleeding due to DAPT Following ...
As a result of the direct pharmacologic effects of DAPT, gastrointestinal bleeding (GIB) occurs as a complication in at least 0.6–3.9% of ...
#11. Continued DAPT after PCI Increases Risk of GI Injury and ...
Despite being at low bleeding risk, gastrointestinal (GI) mucosal injury was detected in most patients undergoing percutaneous coronary ...
#12. Acute GI Bleeding After Percutaneous Coronary Intervention
Patients who have undergone emergent PCI after STEMI and suffer a GI bleed will typically be receiving anticoagulants such as UFH, enoxaparin or ...
#13. Risk and management of upper gastrointestinal bleeding ...
The use of dual-antiplatelet therapy (DAPT) with aspirin ... site of GI bleeding and a potential target for preventative strategies.
#14. Gastrointestinal Injury Caused by Aspirin or Clopidogrel ...
Unfortunately, DAPT approximately doubles the risk of gastrointestinal (GI) bleeding compared with single antiplatelet therapy (SAPT) (2).
#15. Original article Proton Pump Inhibitors and In-Hospital ...
Conclusion. In China, PPIs are widely used within 24 hours of admission in patients with ACS taking DAPT. An increased risk of GI bleeding is ...
#16. Magnetic Endoscopy Capsule Reveals GI Damage Surprises ...
The good news is that, despite the GI signals, clinically overt GI bleeding was rare with both DAPT and single antiplatelet therapy (SAPT) ...
#17. Acute Coronary Syndrome, Antiplatelet Therapy, and Bleeding
Gastrointestinal Bleeding. The most common serious DAPT related bleeding complication after PCI is GI haemorrage [68,69]. Aspirin causes GI bleeding due to its ...
#18. Should patients on DAPT after ACS receive prophylactic PPIs?
However, among patients on DAPT after recent PCI, the incidence of GI bleeding is 2.7%, and those patients with GI bleeds have significantly ...
#19. ANTIPLATELETS, ANTICOAGULANTS AND BLEEDING RISK
Upper GI inflammation (and of course previous GI bleeding) ... (DAPT)) or an anticoagulant plus and antiplatelet treatment (known as ...
#20. Etiology of Gastrointestinal Bleeding in ... - ResearchGate
Background: Dual antiplatelet therapy (DAPT) is associated with an increased risk of gastrointestinal bleeding (GIB). Traditionally thought to cause mostly ...
#21. When to Restart Antithrombotic Therapy After a ...
Gastrointestinal (GI) bleeding is common in patients who receive antithrombotic agents for vascular concerns. When GI bleeding occurs, ...
#22. Gastrointestinal Damage Nearly Universal With Antiplatelet ...
Noninvasive endoscopy in OPT-PEACE reveals surprises about GI effects ... Ultimately, DAPT was associated with more GI bleeding at 12 months ...
#23. Co-prescription of Dual-Antiplatelet Therapy and Proton Pump ...
According to ACCF/ACG/AHA guidelines, patients on DAPT with multiple risk factors for GI bleeding can appropriately be prescribed PPI. The use ...
#24. SECONDARY PREVENTION AFTER ACS
ANTITHROMBOTIC TREATMENT: Switching between P2Y12 inhibitors for DAPT after ACS (1) ... of upper GI bleeding Reinitiate DAPT as soon as deemed safea.
#25. PWE-188 Do proton pump inhibitors prevent upper ... - Gut
DAPT carries a risk of gastrointestinal (GI) bleeding. The incidence and outcome of patients who have a GI bleed whilst taking DAPT are not well known and ...
#26. Dual Antiplatelet Therapy after PCI in Patients at High ...
Dual Antiplatelet Therapy after PCI in Patients at High Bleeding Risk ... (Funded by Terumo; MASTER DAPT ClinicalTrials.gov number, ...
#27. Gastrointestinal bleeding in patients with Helicobacter pylori ...
Upper gastrointestinal bleeding leads to increased morbidity, mortality, and discontinuation of DAPT with consequent failure of adequate ...
#28. The Role of Proton Pump Inhibitors for GI Bleed Prophylaxis in ...
As the role and utilization of dual antiplatelet therapy (DAPT) increases, the rate of gastrointestinal (GI) bleeding events are also expected ...
#29. Single antiplatelet therapy causes less GI injury, bleeding than ...
SAPT resulted in less GI mucosal injury though 12 months compared with DAPT (94.3 percent vs 99.2 percent; p=0.02). Similar effects were ...
#30. Trial examines differences in gastrointestinal effects of ...
Dual antiplatelet therapy (DAPT) followed by single anti-platelet therapy (SAPT) ... GI bleeding is the most frequent major complication of ...
#31. Proton Pump Inhibitors Are Underprescribed in Patients ...
treatment with dual antiplatelet therapy (DAPT) is standard of care. ... risk of gastrointestinal (GI) bleeding in patients who require.
#32. Antiplatelet therapy with or without PPIs for the secondary ...
For patients at high GI risk who have previous major upper gastrointestinal (UGI) complications of peptic ulcer, UGI bleeding or perforation and ...
#33. Journal of Cardiology
factors for GI bleeding include a history of bleeding or other complications of peptic ulcer ... antiplatelet therapy (DAPT)] [1,16–19].
#34. Clinical Outcomes of Concomitant Use of Proton Pump ...
Conclusion: The use of PPIs was associated with a reduced risk of GI bleeding in patients treated with DAPT after percutaneous coronary i...
#35. Management of Simultaneous Overt Gastrointestinal Bleeding
Keywords: upper gastrointestinal bleeding, acute coronary syndrome, ... DAPT aims to reduce the activation of platelets and inhibit their ...
#36. Which One Can be Continued During Gastrointestinal Bleeding
DAPT consists of aspirin and P2Y12 receptor inhibitor (e.g. clopidogrel), and the use of DAPT has been increased over time. The most serious and common adverse ...
#37. Antiplatelet agents in uncertain clinical scenarios—a bleeding ...
Keywords: Antiplatelet; dual antiplatelet therapy (DAPT); bleeding; elderly; ... Strikingly, major GI bleeds, in patients over 75 years on DAPT are ...
#38. When Should Antiplatelet Agents and Anticoagulants Be ...
Risks for GI bleeding include older age, history of peptic ulcer disease, NSAID or steroid use, and the use of antiplatelet or anticoagulation ...
#39. Proton Pump Inhibitors and the Prevention of Recurrent GI ...
The risk of GI bleeding with clopidogrel monotherapy is generally low; ... Dual antiplatelet therapy (DAPT) with clopidogrel and aspirin was ...
#40. Risk of Gastrointestinal Bleed and Endoscopic Procedures on ...
The odd's ratio of serious GI bleed with aspirin, clopidogrel, and dual antiplatelet therapy (DAPT) according to a population‑based study.
#41. 409 Factors Relating to GI Bleeding Induced by Dual ...
409 Factors Relating to GI Bleeding Induced by Dual Antiplatelet Therapy (DAPT) in Japanese Patients With Percutaneous Coronary Intervention - Retrospective ...
#42. 비정맥류 상부위장관 출혈 2018 아시아-태평양 가이드라인 소개
NVUGIB, non-variceal upper gastrointestinal bleeding; DAPT, dual antiplatelet therapy; DOACs, direct oral anticoagulants.
#43. Major bleeding risk and mortality associated with ... - PLOS
In dual therapy, the risk of major non-fatal bleeding is increased whatever the dual antiplatelet regimen [12]. Major bleedings other than GI ...
#44. Scenario: Secondary prevention of CVD | Antiplatelet treatment
For people at high risk of bleeding, continue DAPT for at least one month. ... disease or upper GI bleeding, unless previously tested and treated for this.
#45. Combining antiplatelet and anticoagulant therapy in ...
... upper gastrointestinal bleeding risk in select populations. ... plus DAPT (triple therapy). 8 As might be expected, any bleeding was less ...
#46. Risk Factors for Gastrointestinal Injuries in Acute Coronary ...
Further, these studies focused on GI bleeding, especially UGIB, which is only one possible outcome of GI injury. It is important to evaluate the impact of DAPT ...
#47. A practical guide on how to handle patients ... - Europe PMC
Despite the bleeding risk, dual antiplatelet therapy (DAPT), ... upper gastrointestinal bleeding, to continue aspirin or DAPT if endoscopy shows no active ...
#48. 2015_s_0034_1393172.pdf - European Society of ...
per gastrointestinal (GI) hemorrhage/bleeding, peptic ulcer he- ... patients receiving dual antiplatelet therapy (DAPT) who develop peptic ulcer bleeding, ...
#49. No Differences in Gastrointestinal Bleeding Risk among ...
Dual antiplatelet therapy (DAPT) is more effective than aspirin (ASA) alone in the ... The risk of gastrointestinal bleeding in patients.
#50. 708FM.5.1 ANTIPLATELETS AND RIVAROXABAN 2.5 mg ...
Duration of dual antiplatelet therapy (DAPT) or single antiplatelet plus rivaroxaban 2.5 mg ... Gastrointestinal (GI) bleeding risk assessment for DAPT:.
#51. Acute Coronary Syndrome, Antiplatelet Therapy, and Bleeding
PCI, percutaneous coronary intervention; DAPT, dual antiplatelet therapy; ACS, ... GI bleeding receiving DAPT after ACS [71].
#52. Provision of Gastroprotective Medication and Bleeding Risk ...
A retrospective analysis aims to determined whether high bleeding risk acute coronary syndrome patients taking DAPT were appropriately provided with GI ...
#53. Gastrointestinal Bleeding Etiologies, Management, and the ...
and differentiate upper GI bleeding, small bowel bleeding, and ... (DAPT). Aspirin +. Antiplatelet. Agent +. Anticoagulant. Upper GI. Bleeding NNH. (95% CI).
#54. Endoscopy in patients on antiplatelet or anticoagulant therapy
dual antiplatelet therapy (DAPT) (strong recom- ... increase in postprocedure GI bleeding and thromboembolism in.
#55. Magnetically controlled capsule endoscopy detects GI injury ...
Researchers also observed less gastrointestinal bleeding among patients taking single antiplatelet therapy compared with DAPT (0.6% vs.
#56. Dual antiplatelet therapy for secondary stroke prevention
A PPI should be used in patients taking DAPT who are at high risk of GI bleeds to help reduce the risk of major bleeding.19-21 If DAPT is used, there is limited ...
#57. Study Examines Differences in Gastrointestinal Effects of ...
Dual antiplatelet therapy (DAPT) followed by single anti-platelet therapy (SAPT) ... GI bleeding is the most frequent major complication of ...
#58. a systematic literature review and patient preference elicitation ...
Dual antiplatelet therapy (DAPT) is the recommended preventative treatment for secondary ischaemic events, but increases the risk of bleeding, ...
#59. Treatment of Acute Nonvariceal Upper Gastrointestinal ...
Treatment of Acute Nonvariceal Upper Gastrointestinal Bleeding in ... all antithrombotic agents should be stopped and the need for DAPT or ...
#60. Study examines differences in gastrointestina | EurekAlert!
Dual antiplatelet therapy (DAPT) followed by single anti-platelet therapy (SAPT) ... GI bleeding is the most frequent major complication of ...
#61. Upper GI Bleeding in the Era of DOACs
Upper GI Bleeding in the Era of DOACs: ... Aspirin+clopidogrel (DAPT) in acute coronary syndrome. N Engl J Med. ... VKA versus DAPT in atrial fibrillation.
#62. TCT 2021: Endoscopy study could have implications for post ...
GI bleeding is the most frequent major complication of ... at low risk for bleeding were enrolled following PCI and six months of DAPT.
#63. Reducing Gastrointestinal Bleeding due to DAPT Following ...
The combination of aspirin and thienopyridines that constitute DAPT ... with a history of prior gastrointestinal (GI) bleeding who require DAPT Use of PPIs ...
#64. Makin ng Gold ilocks H Happy - RxFiles
- ↑ risk of bleeding with prasugrel & ticagrelor (ticagrelor CI if history of intracranial bleed). GASTROPROTECTION ½ to ⅔ of bleeds caused by DAPT are GI ...
#65. Major bleeding risk and mortality associated with antiplatelet ...
The main outcome measure was time to major bleeding (GI, ... Mauri L, Elmariah S, Yeh RW, et al., for the DAPT study investigators.
#66. Magnetically Controlled Capsule Endoscopy in GI Injury
Clinical gastrointestinal bleeding between 6 and 12 months was less with SAPT compared with DAPT (0.6% vs. 5.4%, P=0.001).
#67. Most PCI Patients on Antiplatelet Therapy Developed ...
Dual antiplatelet therapy (DAPT) followed by single anti-platelet therapy (SAPT) ... GI bleeding is the most frequent major complication of ...
#68. Management in the Upper Gastrointestinal Bleeding Patient
Non-variceal upper GI bleeding: Patient on DAPT. APAGE-APSDE: continue aspirin, withhold second antiplatelet agent.
#69. COGENT - PPI added to DAPT in patients after ACS/PCI
PPIs should be mandatory in those with prior GI bleed while taking dual antiplatelet therapy unless contraindicated.
#70. Proton Pump Inhibitors (PPIs) and antiplatelet therapy ...
A high dose of aspirin. • A history of gastroduodenal ulcer, GI bleeding, or gastroduodenal perforation. • Concomitant use of medications that are known to ...
#71. Management of Nonvariceal Upper Gastrointestinal Bleeding
Acute upper gastrointestinal bleeding (UGIB) is common, but the annual ... the use of PPIs in patients receiving DAPT who had a history of ulcer bleeding.
#72. antiplatelet therapy - Canadian Cardiovascular Society
risk of bleeding, it is reasonable to extend the duration of DAPT to ... against gastro-intestinal bleeding while patients are on a triple therapy regimen.
#73. Association of Ticagrelor vs Clopidogrel With Major Adverse ...
Secondary outcomes included hospitalization for major bleeding and ... was mainly driven by an increase in gastrointestinal hemorrhage (aHR, ...
#74. Use of DAPT Score in Malaysian Population - International ...
The mean time on dual anti-platelet is for the high DAPT score was 14 months ... In the high DAPT score group, there were 4 patients who had upper GI bleed, ...
#75. Proton Pump Inhibitors and In-Hospital Gastrointestinal ...
gastrointestinal (GI) bleeding in patients with acute coronary syndrome (ACS) taking dual anti- platelet therapy (DAPT). Patients and Methods: This study is ...
#76. EVOLVE Short DAPT Study - Full Text View - ClinicalTrials.gov
Subject has an active peptic ulcer or active gastrointestinal (GI) bleeding; Subject is participating in an investigational drug or device clinical trial that ...
#77. Stemi Management in a Patient With Anemia and Occult GI ...
STEMI Management in a Patient With Anemia and Occult GI Bleeding: What is the ... (POBA) + ASA for 12 months; II: BMS + DAPT for 1 month, ...
#78. When can I stop dual antiplatelet therapy in patients with drug ...
Therefore, a proton pump inhibitor should be started along with DAPT in patients at high risk of gastrointestinal bleeding.
#79. In CAD with GI bleeding, higher mortality with triple therapy
In CAD with GI bleeding, higher mortality with triple therapy ... thienopyridine (dual antiplatelet therapy [DAPT]; 25 percent); or aspirin, ...
#80. Gastroprotective Effects of PPIs, H2RAs Compared in Patients ...
... (GI) complications in patients on dual antiplatelet therapy (DAPT), ... used to reduce the risk of GI bleeding in patients on DAPT, ...
#81. Upper GI Bleeding on Anticoagulants and Antiplatelets
#82. Triple Therapy in Coronary Artery Disease With GI Bleeding ...
Triple Therapy in Coronary Artery Disease With GI Bleeding May Increase ... antiplatelet therapy [DAPT]; 25%); or aspirin, thienopyridine, ...
#83. MASTER DAPT trial: Dual antiplatelet therapy after coronary ...
#84. Dapt duration - SlideShare
... ,DAPT and oral anticoagulants,invidualised antiplatelet therapy,ppi. ... of OAC -Age -History of bleeding -Low body weight -ACS -Thrombocytopenia -GI ...
#85. New ACG Lower GI Bleeding Guideline - American College of ...
Hematochezia associated with hemodynamic instability may be indicative of an upper gastrointestinal (GI) bleeding source and thus warrants ...
#86. Antiplatelet therapy in coronary artery disease - Straight ...
DAPT is recommended after PCI to prevent stent thrombosis and myocardial infarction. DAPT also increases the risk of significant bleeding. The length of DAPT ...
#87. Duration of dual antiplatelet therapy after PCI - empendium.com
The DAPT trial took 10,000 patients who had completed a year of dual antiplatelet therapy and if they had not had any bleeding or ischemic ...
#88. Dual anti - platelet therapy - 醫學筆記匯集整理ED Notes
Dual Antiplatelet Therapy (DAPT) : 定義為Aspirin(ASA) + P2Y12 receptor inhibitor (clopidogrel, prasugr.
#89. MASTER DAPT: dual antiplatelet therapy after coronary ...
What should we do for the long-term treatment of high-bleeding risk (HBR) patients who completed the DAPT regimen? Restart life-long aspirin ...
#90. GI Endoscopic Emergencies - 第 45 頁 - Google 圖書結果
Warfarin combined with DAPT increases the risk of GI bleeding substantially, with a hazard ratio (HR) of 5.0 (1.4–17.8) relative to DAPT alone in one study ...
#91. Clinical Cardiology: Current Practice Guidelines
III-B-NR PPIs PPIs should be used in patients with a history of prior GI bleeding who require DAPT. I-C Use of PPIs in patients with an increased risk of GI ...
#92. Antiplatelet and Anticoagulation Therapy In PCI, An Issue of ...
There is emerging evidence surrounding the potential role of proton pump inhibitors (PPI) in reducing gastrointestinal (GI) bleeding in patients on DAPT.42 ...
dapt gi bleeding 在 MASTER DAPT trial: Dual antiplatelet therapy after coronary ... 的美食出口停車場
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