關於 cancer cell international ，我們在網路上蒐集到這些相關的討論、資訊與評價

嗨，你是「對的人」嗎？
♥️ Be a match, save a life!
(See English version below)

大家好，這是一篇貨真價實的·救命·帖。
當我們在煩惱下一頓飯吃什麼時，我有一位好朋友正在煩惱怎麼對抗病魔。

急性白血病（又稱急性血癌）不是省油的燈。
治療過程既有百米賽跑的intensity，又有馬拉松式的漫長。
她表現得很好，可以笑的時候不會哭，可以大聲的時候不會小聲。
一輪輪的化療、感染治療，她都挺過來了（擦淚）。

這位女神姐姐現在需要找一樣東西
不是玻璃鞋或白馬王子
而是那個與她匹配的骨髓，可以讓她續命活血，健健康康的「骨髓」。

這個救命的骨髓可能就在你身上！
幫幫忙，你可以去check下，你身上的骨髓適不適合她嗎？

❓做麼我要去咧？
✔️ 從健康的個體移植的骨髓 / 幹細胞，可用來救治多種血液相關疾病患者。
疫情期間，國外骨髓捐贈者難求，只得求助於國內自願捐贈者。但馬來西亞的幹細胞捐贈者人數偏低，降低了匹配率。

❓我符合資格嗎？
✔️ 任何年紀介於 18 - 50 歲的馬來西亞公民，只要沒有重大疾病，都可以註冊成為骨髓自願捐贈者。

❓我要做什麼咧？
✔️ 拿起手機，撥電給馬拉西亞幹細胞登記處（03-26162790 / 03-26162780），提前預約骨髓測試。
測試結果會被登記處存檔，如果您是一位骨髓匹配的捐贈者，登記處將再聯繫您。

🌟

As you might be aware, I have a lovely friend who is battling with acute myeloid leukemia (AML), or in simple terms: blood cancer.

Our Princess Annie is now looking for someone.
Not a prince charming 🤴🏻
but a matching donor for her bone marrow transplant.
Are you the one in the million who could join her in this battle? 🦸🏻‍♀️🦸🏻‍♂️

Get a test and register yourself as a stem cell donor.
You could save Annie's life or any other‘s!

❓Why should I do so?
✔️The blood stem cells transplantation from healthy individuals to patients suffering from blood-related diseases can help patients to recover and become healthy again.
It is relatively difficult to get international donors during pandemic and the number of registered stem cell donors marks low in Malaysia.

❓Am I eligible?
✔️ Any Malaysian aged 18-50 and free from chronic diseases, can register as a donor volunteer

❓What should I do?
✔️ Call the Malaysian Stem Cell Registry (MSCR) at 03-26162790 / 03-26162780 to make an early appointment for Buccal Swab test. You will be informed if you are a matching donor.

I can't thank you enough for reading this post. Feel free to share this with your friends and family! ❤️

Stay safe and spread love!

🚭不抽菸怎還會得肺癌？


肺癌是全球癌症死亡的主因，即使藥物治療近年有長足的進展，5年存活率仍低於20％，目前仍是國人癌症死亡頭號殺手😱

‼本院最新研究：臺灣有一半以上的肺癌病患並不吸菸，超過 9 成得肺癌的女性也都不抽菸，與 #體內酵素突變 大有關係，而且近十年有年輕化的趨勢，研究成果發表在🌏國際期刊《細胞》《Cell》上，並榮登本期封面‼

_______________________________

本院化學所陳玉如特聘研究員、臺大醫學院內科教授楊泮池（本院院士）與跨單位研究團隊以 #蛋白基因體技術 建立東亞第一套結合深度多體學大數據及完整臨床資料，深度解析 #不吸菸肺癌患者 可能的致病機制，研究有三個重要發現⭐⭐⭐

#發現一
✅肺癌與人體內酵素APOBEC 突變特徵的高低有關
罹肺癌患者中，74％從未吸菸年輕女性（小於60歲）和所有無肺癌表皮生長因子受體（EGFR） 突變的女性患者的APOBEC突變特徵程度較高，可能為女性早期肺癌的驅動因素，可能成為早期診斷和免疫治療的潛在生物標誌物。

#發現二
✅與生活中致癌物有關
暴露於致癌物（吸菸、毒化物、油煙、防腐劑、空汙、金屬化合物等）也會引起基因突變，其中年長女性（大於70歲）突變程度較高。化學致癌物代謝和解毒過程及特定途徑的活化可能影響腫瘤癌化、惡化和免疫調節異常。不過確切致癌物分子有待未來進一步研究鑑定。

#發現三
✅發現新亞型肺癌，透過惡性特徵發現早期罹癌患者
臺灣肺癌患者在EGFR基因上會發生Del19和L858R二種突變，若發生L858R突變，存活率較低。此次將肺腺癌分為五個亞型，其中有一個從未被發現的「類晚期」亞型的早期肺癌。此亞型可區分二種突變的的 #惡性特徵　差異。因此，臨床醫師未來有機會可藉判斷有無此類惡性特徵，發現早期肺癌患者，提供密集觀察和選擇適合佐劑加以治療。
　　　　　　　　　　　　　　　
此次成果為臺美合作「癌症登月計畫」的重要里程碑，是美國臨床蛋白基因體學腫瘤分析聯盟（CPTAC）#首次 和國際聯盟團隊（臺灣）攜手合作發表研究成果。透過跨國族群癌症病人的大數據分享及比較，可更精確探討亞洲非抽菸族群致癌機制、檢測及治療的線索，加速癌症精準醫療的實現。除中研院之外，由臺灣大學、臺北醫學大學、臺中榮總提供病人檢體、臨床數據及檢測技術等。研究經費主要來自科技部、中研院及臺灣大學。

#中研院 #化學所 #陳玉如 #癌症登月計畫
#東亞第一套解析不抽菸肺腺癌之多體學大數據
#肺癌 #蛋白基因體 #APOBEC #Cell #封面

🔺論文全文：https://reurl.cc/626v1y
🔺更多細節：https://www.sinica.edu.tw/ch/news/6591
____________________________________

Two new studies released July 9th, 2020 in Cell unravel the biology of lung adenocarcinoma (LUAD) using a suite of molecular techniques that, combined, provide a more complete picture of the disease than ever before. Using a diverse cohort of smokers and non-smokers, male and female, from around the world, researchers from the Clinical Proteomic Tumor Analysis Consortium (CPTAC) and the International Cancer Proteogenome Consortium (ICPC) draw out a clearer understanding of LUAD tumor progression, identify biomarkers, and propose alternative therapeutic targets.

Although strongly associated with smoking, significant populations of never-smokers also develop lung cancer. While never-smokers account for approximately 20% of lung cancer patients in the United States, in Taiwan more than 50% of patients are never-smokers, and many with early onset of the disease. The high number of East Asian LUAD never-smokers presented an opportunity for the ICPC-Taiwan team, led by Drs. Yu-Ju Chen and Pan-Chyr Yang with colleagues from Academia Sinica, National Taiwan University, Taipei Medical University, Taiwan and The Institute of Cancer Research, UK, to take a closer look at the mechanisms of this disease in 103 East Asian patients with a focus on early stage.

🔺More: https://reurl.cc/0o3aAA

#lungadenocarcinoma #LUAD #CPTAC #ICPC #AcademiaSinica #AS #Lungcancer

<醫藥生技資訊>國研院攜手易華、久元開發卵巢癌檢測 獲20億元訂單

#精準醫療 #快速篩查卵巢癌細胞 #子宮內膜癌 #子宮頸癌 #循環腫瘤細胞 #稀有細胞擷取分析系統 #AI人工智慧 #FDA

搶攻全球精準醫療商機，國研院儀科中心攜手醫華生技、久元電子，製作出可快速篩查卵巢癌細胞的生醫檢測平台，獲得開發新藥與細胞治療技術的麗寶生醫公司3年20億元採購訂單。

該產品兩年內已經在臺安醫院與彰化基督教醫院共完成超過600例的癌症細胞樣本數先期分析。

在女性生殖器官的癌症中，卵巢癌的發生率位居第三名，前二名依序是子宮內膜癌及子宮頸癌；但卵巢癌的死亡率卻是第一名，也因此被稱為隱形殺手，主要的原因包括早期診斷困難、腫瘤很快轉移、復發率高等。

國際婦科癌症協會（International Gynecologic Cancer Society, IGCS）指出，卵巢癌每年的罹患人數直線攀升，每年皆有25萬的新案例發生，因此如何進行有效的癌症篩檢與癒後追蹤，成為一個重要的課題，而利用「循環腫瘤細胞」的檢測技術已成為近年來最夯的新興篩檢方法。

所謂的「循環腫瘤細胞」，就是隨著腫瘤的生長，有一部分腫瘤細胞從原發腫瘤上脫落，進入血液系統或淋巴系統，循環到體內的各個部位，會增生出更多的腫瘤細胞，進而形成新腫瘤。若「循環腫瘤細胞」的數量越多，則表示癌細胞本身較具侵略性及癒後較差，因此準確知道「循環腫瘤細胞」的種類與數量，對癌症診斷與癒後監控非常有幫助。可想而知，要從1cc的血液、數十億紅血球中找到約只有1到10顆循環腫瘤細胞，就像大海撈針一樣非常困難。

醫華董事長黃忠諤指出，醫華開發的「稀有細胞擷取分析系統」，是一種新式單細胞捕捉、分離與分析技術，該技術利用全自動化的操作平台及標準化檢測流程，結合架構於生醫晶片的陣列型微結構來辨識及捕捉目標細胞，可以有效地在大海中找到那根針，也就是「循環腫瘤細胞」。此外，醫華生技再透過AI人工智慧，以少量血液即可快速有效地分析目標細胞，因此提高了技術的優勢，成為提供癌症細胞檢測平台的領先廠商。

根據全球市場研究機構TrendForce及Persistence Market Research調查報告顯示，2018年全球醫療器材市場規模估達4,442億美元，2023年上看5,776億美元；其中全球精準醫療市場規模在2024年預估達到1,729億美元，產值並將持續攀升，是一個非常有發展前景的產業鏈。

由於「循環腫瘤細胞」的檢測技術具有高技術含量，過去15年（2004~2019）全世界僅Cell Search一家公司通過美國食品藥物管理局（FDA）許可上市。目前醫華生技的生醫檢測平台正在申請衛生福利部食品藥物管理署認證，未來也打算申請美國FDA認證。

2019-07-25 工商時報 / 杜蕙蓉報導

資料來源：
https://ctee.com.tw/news/industry/123099.html

The Yang family have spent years in and out of hospitals with their two children Jerry and Lillian – both battling Leukemia and needing a blood stem cell transplant. Jerry was lucky enough to have a match on the Be The Match registry. Ruko donated marrow to him 5 years ago and they were able to meet for the first time!

Lillian, unfortunately, does not have any matches on the Be The Match registry and needs to find a life-saving blood stem cell donor.

Sign up today and give someone like Lillian a second chance at life.”

For information and registration, Text DanLok to 61474 or visit BeTheMatch.org/DanLok

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Dan Lok has been viewed more than 1.7+ billion times across social media for his expertise on how to achieve financial confidence. And is the author of over a dozen international bestselling books.

Dan has also been featured on FOX Business News, MSNBC, CBC, FORBES, Inc, Entrepreneur, and Business Insider.

In addition to his social media presence, Dan Lok is the founder of the Dan Lok Organization, which includes more than two dozen companies - and is a venture capitalist currently evaluating acquisitions in markets such as education, new media, and software.

Some of his companies include Closers.com, Copywriters.com, High Ticket Closers, High Income Copywriters and a dozen of other brands.

And as chairman of DRAGON 100, the world’s most exclusive advisory board, Dan Lok also seeks to provide capital to minority founders and budding entrepreneurs.

Dan Lok trains as hard in the Dojo as he negotiates in the boardroom. And thus has earned himself the name; The King of Closing.

If you want the no b.s. way to master your financial destiny, then learn from Dan. Subscribe to his channel now.

★☆★ CONNECT WITH DAN ON SOCIAL MEDIA ★☆★
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#BeTheMatch #Donor

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This video is about Young Leukemia Survivor Meets Life-Saving Donor For The First Time (Live).

https://youtu.be/CNvguP1GB2o
https://youtu.be/CNvguP1GB2o